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DESCRIPTION
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DESCRIPTION
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Package: miqtl
Title: Suite of QTL Mapping Functions
Version: 1.1.2
Authors@R: c(person("William", "Valdar", role = "aut"),
person("Robert", "Corty", role = "aut"),
person("Gregory", "Keele", email = "[email protected]", role = c("aut", "cre")))
Description: This package contains a number of useful QTL mapping utilities. It supports single locus modeling in terms of haplotype descent and SNPs. These methods make use of a genome cache directory that contains information on haplotype descent for all individuals at all loci in a specific file setup. For haplotypes, both regression-on-probabilities (ROP) and multiple imputations are possible. For SNPs, dosages (imputation from haplotypes - in the human GWAS sense) are used. An invertible relationship matrix can be used to include a random effect. Exact and approximate (estimation of variance components only under the null model) analysis are possible. For haplotype analysis, weights can be included on the error covariance matrix.
Depends: R (>= 3.2.2)
License: GPL (>= 2)
Encoding: UTF-8
LazyData: true
RoxygenNote: 7.1.1
Imports: Matrix, mnormt, gdata, evir, data.table
Suggests: plotrix, scales, DOQTL, lme4, EnvStats