NTR-border-associated-macrophage (#2319)

* NTR-border-associated-macrophage Fixes #2285 * Update cl-edit.owl * Update cl-edit.owl * Update cl-edit.owl * Update cl-edit.owl * Update cl-edit.owl * Update cl-edit.owl * Update cl-edit.owl
obophenotype · Apr 4, 2024 · 610d386 · 610d386
1 parent bdd46bb
commit 610d386
Showing 1 changed file with 66 additions and 12 deletions.
diff --git a/src/ontology/cl-edit.owl b/src/ontology/cl-edit.owl
@@ -3026,6 +3026,10 @@ Declaration(Class(obo:CL_4040005))
 Declaration(Class(obo:CL_4040006))
 Declaration(Class(obo:CL_4042001))
 Declaration(Class(obo:CL_4042002))
+Declaration(Class(obo:CL_4042003))
+Declaration(Class(obo:CL_4042004))
+Declaration(Class(obo:CL_4042005))
+Declaration(Class(obo:CL_4042006))
 Declaration(Class(obo:CP_0000000))
 Declaration(Class(obo:CP_0000025))
 Declaration(Class(obo:CP_0000027))
@@ -11263,26 +11267,31 @@ SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000878 obo:CL_0000864
 
 # Class: obo:CL_0000879 (meningeal macrophage)
 
-AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:ana") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMID:11591794") obo:IAO_0000115 obo:CL_0000879 "A central nervous system macrophage found in the meninges (the three membranes that surround the brain). This macrophage types is highly phagocytic and expresses scavenger receptors.")
+AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:ana") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMID:11591794") Annotation(oboInOwl:hasDbXref "PMID:24078900") Annotation(oboInOwl:hasDbXref "PMID:37232741") obo:IAO_0000115 obo:CL_0000879 "A border associated macrophage that is part of a meninx. This macrophage type is elongated and amoeboid spindle-shaped with limited mobility. This macrophage is highly phagocytic, expresses scavenger receptors, has dynamic protrusions and extends its processes during inflammation.")
+AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:33556248") oboInOwl:hasExactSynonym obo:CL_0000879 "subdural leptomeningeal macrophage")
+AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:28323268") oboInOwl:hasExactSynonym obo:CL_0000879 "subdural meningeal macrophage")
+AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:33556248") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_0000879 "MM")
+AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:38347231") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_0000879 "MnMΦ")
+AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:37232741") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_0000879 "sdΜΦ")
 AnnotationAssertion(rdfs:label obo:CL_0000879 "meningeal macrophage")
-EquivalentClasses(obo:CL_0000879 ObjectIntersectionOf(obo:CL_0000878 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002360) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0005044)))
-SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000879 obo:CL_0000878)
+EquivalentClasses(obo:CL_0000879 ObjectIntersectionOf(obo:CL_4042003 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002360) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0005044)))
+SubClassOf(obo:CL_0000879 obo:CL_4042003)
 
-# Class: obo:CL_0000880 (choroid-plexus macrophage)
+# Class: obo:CL_0000880 (choroid plexus macrophage)
 
-AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:ana") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMID:9550136") obo:IAO_0000115 obo:CL_0000880 "A central nervous system macrophage found at the interface between the blood and the cerebrospinal fluid in the brain. This cell expresses scavenger receptors.")
-AnnotationAssertion(rdfs:label obo:CL_0000880 "choroid-plexus macrophage")
-EquivalentClasses(obo:CL_0000880 ObjectIntersectionOf(obo:CL_0000878 ObjectSomeValuesFrom(obo:RO_0001025 obo:UBERON_0001886) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0005044)))
-SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000880 obo:CL_0000878)
+AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:ana") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMID:37232741") Annotation(oboInOwl:hasDbXref "PMID:9550136") obo:IAO_0000115 obo:CL_0000880 "A border associated macrophage found at the interface between the blood and the cerebrospinal fluid in the brain. This central nervous system macrophage has a star-like shaped body and expresses scavenger receptors.")
+AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:37232741") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_0000880 "cpMΦ")
+AnnotationAssertion(rdfs:label obo:CL_0000880 "choroid plexus macrophage")
+EquivalentClasses(obo:CL_0000880 ObjectIntersectionOf(obo:CL_4042003 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001886) ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0005044)))
 
 # Class: obo:CL_0000881 (perivascular macrophage)
 
-AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMID:16507898") obo:IAO_0000115 obo:CL_0000881 "A central nervous system macrophage found in small blood vessels in the brain. Markers include CD14+CD16+CD163+.")
-AnnotationAssertion(rdfs:comment obo:CL_0000881 "Markers: Human/monkey, mice: CD163. Human: CD14+CD16+CD163+.")
+AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "GO_REF:0000031") Annotation(oboInOwl:hasDbXref "PMID:16507898") Annotation(oboInOwl:hasDbXref "PMID:37232741") obo:IAO_0000115 obo:CL_0000881 "A border associated macrophage that is adjacent to a small blood vessel of a brain. A perivascular macrophage expresses the markers CD14, CD16 and CD163. In homeostatic conditions, this central nervous system macrophage has a non-motile cell body with extending and retracting projections through the blood vessel wall.")
+AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:37232741") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_0000881 "pvMΦ")
 AnnotationAssertion(rdfs:label obo:CL_0000881 "perivascular macrophage")
-EquivalentClasses(obo:CL_0000881 ObjectIntersectionOf(obo:CL_0000878 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001981) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001483) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001889) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001925)))
-SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000881 obo:CL_0000878)
+EquivalentClasses(obo:CL_0000881 ObjectIntersectionOf(obo:CL_4042003 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001981) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001483) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001889) ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000001925)))
 SubClassOf(obo:CL_0000881 obo:CL_4033054)
+SubClassOf(Annotation(oboInOwl:is_inferred "true") obo:CL_0000881 obo:CL_4042003)
 
 # Class: obo:CL_0000882 (thymic medullary macrophage)
 
@@ -31965,6 +31974,51 @@ AnnotationAssertion(rdfs:label obo:CL_4042002 "TAC3-positive medium spiny neuron
 SubClassOf(obo:CL_4042002 obo:CL_4030051)
 SubClassOf(obo:CL_4042002 ObjectSomeValuesFrom(obo:RO_0002104 obo:PR_000016004))
 
+# Class: obo:CL_4042003 (border associated macrophage)
+
+AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:37232741") Annotation(oboInOwl:hasDbXref "PMID:37626977") obo:IAO_0000115 obo:CL_4042003 "A central nervous system macrophage that is part of a choroid plexus, a meninx and a perivascular space. A border associated macrophage interacts with various components of the CNS vasculature and meninges, it participates in immune surveillance and in the regulation of the blood brain barrier.")
+AnnotationAssertion(<http://purl.org/dc/terms/contributor> obo:CL_4042003 <https://orcid.org/0000-0002-0098-8958>)
+AnnotationAssertion(<http://purl.org/dc/terms/date> obo:CL_4042003 "2024-03-26T16:39:56Z"^^xsd:dateTime)
+AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:36945367") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4042003 "BAM")
+AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:33556248") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4042003 "CAM")
+AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:37232741") oboInOwl:hasRelatedSynonym obo:CL_4042003 "CNS-associated macrophage")
+AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:29426702") Annotation(oboInOwl:hasDbXref "PMID:37232741") rdfs:comment obo:CL_4042003 "In humans, a border associate macrophage expresses CD45 and CD11B. This cell is also known to have the following molecular signature: CD206, CD38, LYVE1, CD163, CD169.")
+AnnotationAssertion(rdfs:label obo:CL_4042003 "border associated macrophage"@en)
+SubClassOf(obo:CL_4042003 obo:CL_0000878)
+
+# Class: obo:CL_4042004 (choroid epiplexus macrophage)
+
+AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:31061494") Annotation(oboInOwl:hasDbXref "PMID:37232741") obo:IAO_0000115 obo:CL_4042004 "A choroid plexus macrophage that is part of the apical surface of some choroid plexus epithelium. This macrophage has a star-like shaped body.")
+AnnotationAssertion(<http://purl.org/dc/terms/contributor> obo:CL_4042004 <https://orcid.org/0000-0002-0098-8958>)
+AnnotationAssertion(<http://purl.org/dc/terms/date> obo:CL_4042004 "2024-03-26T19:14:58Z"^^xsd:dateTime)
+AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:31433571") oboInOwl:hasExactSynonym obo:CL_4042004 "Kolmer’s cell")
+AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:38347231") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4042004 "cpepiMΦ")
+AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:38347231") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4042004 "epiplexus cpMΦ")
+AnnotationAssertion(rdfs:label obo:CL_4042004 "choroid epiplexus macrophage"@en)
+SubClassOf(obo:CL_4042004 obo:CL_0000880)
+SubClassOf(obo:CL_4042004 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0003911))
+
+# Class: obo:CL_4042005 (stromal choroid plexus macrophage)
+
+AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:38347231") obo:IAO_0000115 obo:CL_4042005 "A choroid plexus macrophage that is part of a choroid plexus stroma.")
+AnnotationAssertion(<http://purl.org/dc/terms/contributor> obo:CL_4042005 <https://orcid.org/0000-0002-0098-8958>)
+AnnotationAssertion(<http://purl.org/dc/terms/date> obo:CL_4042005 "2024-03-26T19:21:51Z"^^xsd:dateTime)
+AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:37626977") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4042005 "cpstMΦ")
+AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:37232741") Annotation(oboInOwl:hasDbXref "PMID:38347231") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4042005 "stromal cpMΦ")
+AnnotationAssertion(rdfs:label obo:CL_4042005 "stromal choroid plexus macrophage"@en)
+SubClassOf(obo:CL_4042005 obo:CL_0000880)
+SubClassOf(obo:CL_4042005 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0005206))
+
+# Class: obo:CL_4042006 (dural macrophage)
+
+AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:31061494") obo:IAO_0000115 obo:CL_4042006 "A border associated macrophage which is part of a dura matter. This macrophage phagocytoses intruding pathogens and foreign molecules detected in the bloodstream or in the cerebrospinal fluid. This cell has an amoeboid body with dynamic protrusions in homeostasis.")
+AnnotationAssertion(<http://purl.org/dc/terms/contributor> obo:CL_4042006 <https://orcid.org/0000-0002-0098-8958>)
+AnnotationAssertion(<http://purl.org/dc/terms/date> obo:CL_4042006 "2024-03-26T19:27:03Z"^^xsd:dateTime)
+AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:37232741") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasRelatedSynonym obo:CL_4042006 "dmMΦ")
+AnnotationAssertion(rdfs:label obo:CL_4042006 "dural macrophage"@en)
+SubClassOf(obo:CL_4042006 obo:CL_4042003)
+SubClassOf(obo:CL_4042006 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0002092))
+
 # Class: obo:CP_0000000 (obsolete CP:0000000)
 
 AnnotationAssertion(obo:IAO_0100001 obo:CP_0000000 obo:CL_0017500)