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Laminin enterocyte of colon #2609

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10 changes: 10 additions & 0 deletions src/ontology/cl-edit.owl
Original file line number Diff line number Diff line change
Expand Up @@ -3076,6 +3076,7 @@ Declaration(Class(obo:CL_4047007))
Declaration(Class(obo:CL_4047011))
Declaration(Class(obo:CL_4047012))
Declaration(Class(obo:CL_4047019))
Declaration(Class(obo:CL_4047021))
Declaration(Class(obo:CL_4047051))
Declaration(Class(obo:CL_4047052))
Declaration(Class(obo:CL_4052001))
Expand Down Expand Up @@ -32547,6 +32548,15 @@ AnnotationAssertion(terms:date obo:CL_4047019 "2024-09-24T12:11:09Z"^^xsd:dateTi
AnnotationAssertion(rdfs:label obo:CL_4047019 "early enterocyte"@en)
EquivalentClasses(obo:CL_4047019 ObjectIntersectionOf(obo:CL_0000584 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0013740)))

# Class: obo:CL_4047021 (laminin enterocyte of colon)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:14585148") Annotation(oboInOwl:hasDbXref "PMID:35101094") obo:IAO_0000115 obo:CL_4047021 "An enterocyte located in the epithelium of the large intestine. This cell expresses and interacts with specific laminin isoforms, particularly laminin-332 (composed of α3, β3, and γ2 chains) and laminin-511 (composed of α5, β1, and γ1 chains). Laminin enterocytes of the colon are attached to the basement membrane via hemidesmosomes containing α6β4 integrin, which binds to laminins. This cell exhibits differential expression of laminin chains along the crypt-surface axis")
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These references are not relevant - new references are needed to support the definition.

AnnotationAssertion(terms:contributor obo:CL_4047021 <https://orcid.org/0009-0005-7919-4905>)
AnnotationAssertion(terms:date obo:CL_4047021 "2024-09-24T14:36:31Z"^^xsd:dateTime)
AnnotationAssertion(rdfs:label obo:CL_4047021 "laminin enterocyte of colon"@en)
EquivalentClasses(obo:CL_4047021 ObjectIntersectionOf(obo:CL_1000347 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0013740)))
SubClassOf(obo:CL_4047021 obo:CL_1000347)

# Class: obo:CL_4047051 (small intestine BEST4+ enterocyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:24223998") Annotation(oboInOwl:hasDbXref "PMID:34497389") obo:IAO_0000115 obo:CL_4047051 "An enterocyte of the human small intestine expressing bestrophin-4 (BEST4) calcium-activated ion channels. These enterocytes have a disinctive transcriptomic profile and are scattered through the small intestine epithelium.")
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