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| <?xml version="1.0" encoding="UTF-8"?> | ||
| <Pathway xmlns="http://pathvisio.org/GPML/2013a" Name="Regulation of cytotoxic T cell responses by Malat1 - miR-15/16 circuit " Data-Source="WikiPathways" Version="WP5489_r135477" Author="[Khanspers]" Last-Modified="20240914003302" Organism="Homo sapiens"> | ||
| <Comment Source="WikiPathways-description">Regulation of activation and differentiation of cytotoxic T cells by long non-coding RNA Malat1 (Metastasis Associated Lung Adenocarcinoma Transcript 1) and the microRNA family miR-15/16. | ||
|
|
||
| This pathway model is developed based on Figure 8 in (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10735224/ Wheeler et al).</Comment> | ||
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| <bp:TERM xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" rdf:datatype="http://www.w3.org/2001/XMLSchema#string">cytotoxic T cell</bp:TERM> | ||
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| <bp:DB rdf:datatype="http://www.w3.org/2001/XMLSchema#string">PubMed</bp:DB> | ||
| <bp:TITLE rdf:datatype="http://www.w3.org/2001/XMLSchema#string">The lncRNA Malat1 inhibits miR-15/16 to enhance cytotoxic T cell activation and memory cell formation.</bp:TITLE> | ||
| <bp:SOURCE rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Elife</bp:SOURCE> | ||
| <bp:YEAR rdf:datatype="http://www.w3.org/2001/XMLSchema#string">2023</bp:YEAR> | ||
| <bp:AUTHORS rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Wheeler BD</bp:AUTHORS> | ||
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| <bp:AUTHORS rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Muñoz-Sandoval P</bp:AUTHORS> | ||
| <bp:AUTHORS rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Wong SK</bp:AUTHORS> | ||
| <bp:AUTHORS rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Simeonov DS</bp:AUTHORS> | ||
| <bp:AUTHORS rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Li Z</bp:AUTHORS> | ||
| <bp:AUTHORS rdf:datatype="http://www.w3.org/2001/XMLSchema#string">DeBarge R</bp:AUTHORS> | ||
| <bp:AUTHORS rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Spitzer MH</bp:AUTHORS> | ||
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| <bp:TITLE rdf:datatype="http://www.w3.org/2001/XMLSchema#string">CD28 mediates transcriptional upregulation of the interleukin-2 (IL-2) promoter through a composite element containing the CD28RE and NF-IL-2B AP-1 sites.</bp:TITLE> | ||
| <bp:SOURCE rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Mol Cell Biol</bp:SOURCE> | ||
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